Lester’s Assassination missions in GTA 5 offer one of the most lucrative ways to make money by cleverly manipulating the in-game stock market, specifically the LCN and BAWSAQ exchanges. These missions, given to Franklin by Lester Crest during the story GTA 5 Accounts, involve targeted killings that directly impact the stock prices of certain companies, allowing players to invest strategically and reap massive financial rewards.

The core idea is to use insider knowledge from Lester’s hits to predict which stocks will rise or fall. Each assassination targets a key figure in a corporation, causing that company’s stock to drop while a rival’s stock rises. By investing in the right stocks before or after the missions, players can maximize profits. However, the best returns come from waiting until after the main story is completed, when all three protagonists (Michael, Franklin, and Trevor) have amassed significant capital to invest.

Key Steps for Maximizing Profit:

1. Complete the Main Story First
   It’s crucial to finish the campaign, including the big heist “The Big Score,” before doing most assassination missions. This ensures you have enough money to invest heavily and gain the highest returns.

2. Invest Before or After Each Mission 
   Each assassination affects specific stocks differently. For example:
   - Hotel Assassination: Invest in Betta Pharmaceuticals before the mission, then sell after the stock rises. Afterward, buy Bilkington Research when its stock dips, then sell it once it rebounds.
   - Multi-Target Assassination: Buy Debonaire Cigarettes before the mission, sell after the rise, then invest in Redwood Cigarettes and sell after a big increase.
   - Vice Assassination: Invest in Fruit after the mission and sell when the stock peaks.
   - Bus Assassination: Buy Vapid after the mission and sell once it doubles in value.
   - Construction Assassination: Purchase GoldCoast before the mission and sell after the price rises by about 80%.

3. Use Multiple Characters to Multiply Investments  
   Switch between Michael, Franklin GTA 5 Modded Accounts for sale, and Trevor to invest all their money in the relevant stocks, multiplying your total returns.