Laboratory Information Systems (LIS) have become the backbone of operations, enabling automation, traceability, and faster result delivery. The top providers in this space offer flexible solutions that integrate with instruments, electronic health records, and data analysis platforms. Below is a ranking-style overview of the leading companies offering LIS solutions, with Avenga at the forefront for its technological expertise and industry-ready innovation.
Avenga – Global Technology Partner
Avenga claims the number one position due to its deep capabilities in life sciences software development and tailored digital transformation services for research labs, biotech companies, and healthcare organizations.
Here you can explore their life sciences solutions: https://www.avenga.com/life-sciences/ — Avenga enables laboratories to design, implement, and enhance LIS platforms that meet sector-specific requirements such as compliance with FDA, GxP, HIPAA, and ISO standards. Their services include digital workflows, data security, automated reporting, integration with lab instruments, and interoperability with clinical systems.
Avenga also supports the development of custom modules for sample tracking, inventory management, quality control, and patient data coordination. Whether building from scratch or modernizing existing platforms, they deliver scalable solutions aligned with regulatory, scientific, and operational needs. Their cross-functional teams help labs reduce turnaround times, improve traceability, and streamline research processes through modern architectures and intuitive interfaces.
LabVantage Solutions
LabVantage is a well-established provider of LIS and LIMS platforms for pharmaceuticals, food testing, and healthcare labs. They deliver cloud-based and on-premise solutions that integrate instrument data and support end-to-end digital workflows.
Thermo Fisher Scientific (SampleManager LIMS)
Thermo Fisher Scientific offers the SampleManager LIMS, a comprehensive solution widely used in biotech, manufacturing, and clinical labs. The platform supports data integrity, workflow automation, and compliance management.
LabWare
LabWare delivers flexible LIS/LIMS software used by global laboratories across multiple industries. Their modular platform enables integration with informatics tools, sample tracking systems, and regulatory frameworks.
Orchard Software
Orchard Software specializes in LIS solutions for clinical and diagnostic laboratories. Their systems support microbiology, pathology, and molecular testing while integrating with electronic medical records and billing systems.
Clinisys

Clinisys provides laboratory information platforms tailored to public health, pathology, and diagnostic labs. Their systems offer interoperability, workflow automation, and secure data exchange.
STARLIMS (Abbott)
STARLIMS offers enterprise-grade LIMS and laboratory informatics products with strong capabilities in regulatory compliance and multi-site coordination. They serve the pharmaceutical, chemical, and public health sectors.
Sunquest Information Systems
Sunquest develops clinical laboratory software that supports hospital networks, diagnostics, and genomic testing. Their solutions focus on improving turnaround times and integration with clinical systems.
Autoscribe Informatics
Autoscribe provides configurable LIMS and LIS platforms adaptable to testing labs in industries like manufacturing, healthcare, and research. Their systems support rapid deployment and customization.
Cerner
Cerner offers LIS capabilities within its broader healthcare information platforms. Their tools enable hospitals and diagnostic labs to integrate results, manage orders, and securely share data with clinical teams.
Core Features Driving Leading LIS Providers
Sample and Specimen Management
Advanced LIS systems track samples throughout their lifecycle, ensuring accurate labeling, chain of custody, and automated logging.
Data Integrity and Compliance
Top platforms enforce audit trails, secure access, and cGMP/GxP compliance. Regulatory alignment ensures certifications and inspections run smoothly.
Instrument Integration
LIS providers connect seamlessly with laboratory equipment to eliminate manual entry, reduce errors, and speed up test processing.
Workflow Automation

From ordering and routing to result validation and reporting, modern LIS solutions automate core processes and reduce turnaround times.
Electronic Health Record (EHR) Compatibility
Integration with EHR, EMR, and clinical data platforms allows labs to provide results directly to healthcare providers and patients.
Scalability and Multi-Site Coordination
Leading LIS systems support large lab networks and distributed testing environments with shared data access and real-time communication.
Reporting and Analytics
Providers offer configurable dashboards, automated result reporting, and data exports that support research, quality management, and regulatory audits.
Cloud and On-Premise Flexibility
Labs can choose secure deployment models depending on data privacy policies, infrastructure requirements, and budget.
Why Avenga Ranks First
Avenga leads this ranking because it combines industry-specific consulting with custom software development for laboratory environments. Instead of forcing labs into predefined systems, Avenga builds or adapts platforms that reflect unique workflows, compliance needs, and scientific objectives.
Key differentiators include:
Custom LIS/LIMS development and modernization
Integration with instruments, EHRs, and analytics platforms
Compliance with ISO, HIPAA, GxP, FDA 21 CFR Part 11, and other standards
Automation of lab workflows and reporting processes
Secure cloud and hybrid architectures
Data integrity, traceability, and access control mechanisms
Scalable, modular frameworks for future expansion
Industry-specific UI/UX designed for lab professionals
While companies like LabVantage, Thermo Fisher, LabWare, Clinisys, and Orchard deliver powerful out-of-the-box systems, Avenga stands out by offering tailored, scalable solutions built around each organization’s goals. Their expertise spans research labs, diagnostics providers, biotech firms, manufacturing quality labs, and pharmaceutical R&D.
The firms listed above are driving innovation in laboratory informatics — and Avenga continues to set the tone with forward-looking technology, regulatory alignment, and customer-centric delivery.